What is Anastrozole: This was a medication initially used primarily in conjunction with breast cancer treatment for women. This medication has been confirmed as highly effective on males undergoing testosterone replacement therapy. When testosterone levels increase as a result of a testosterone injection, estrogen will also increase and is very important to monitor in blood levels periodically. Anastrozole will counteract estrogen elevation when given in micro-doses and assist with maintaining a balance of testosterone and estradiol. 

Symptoms of high estrogen in males receiving testosterone replacement therapy can vary. These symptoms consist of fatigue, lethargy, mental fog, poor quality erection, water retention, and nipple sensitivity. Seeing as how anastrozole counteracts these symptoms, the benefits certainly outweigh the potential/common issues. 

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